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1

How Drugs are Developed and Approved by the FDA: Current Process and Future Directions

Ciociola, Arthur A, Cohen, Lawrence B, Kulkarni, Prasad, Kefalas, Costas, Buchman, Alan, Burke, Carol, Cain, Tedd, Connor, Jason, Ehrenpreis, Eli D, Fang, John, Fass, Ronnie, Karlstadt, Robyn, Pambian

Journal:

American Journal of Gastroenterology

Year:

2014

Language:

english

File:

PDF, 168 KB

english, 2014

2

Pompe disease in a Brazilian series: clinical and molecular analyses with identification of nine new mutations

Sueli M. Oba-Shinjo, Roseli da Silva, Fernanda G. Andrade, Rachel E. Palmer, Robert J. Pomponio, Kristina M. Ciociola, Mary S. Carvalho, Paulo S. Gutierrez, Gilda Porta, Carlo D. Marrone, Verônica Mun

Journal:

Journal of Neurology

Year:

2009

Language:

english

File:

PDF, 255 KB

english, 2009

3

Ranitidine bismuth citrate plus clarithromycin is effective for healing duodenal ulcers, eradicating H. pylori and reducing ulcer recurrence. RBC H. pylori Study Group [see comments]

WL Peterson, AA Ciociola, DL Sykes, DJ McSorley, DD Webb

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 298 KB

english, 1996

4

An Alternative Non-Macrolide, Non-Imidazole Treatment Regimen for Curing Helicobacter pylori and Duodenal Ulcers: Ranitidine Bismuth Citrate Plus Amoxicillin

David Y. Graham, Jeffrey R. Breiter, Arthur A. Ciociola, Deborah L. Sykes, David J. McSorley, H. The Rbc Pylori, Study Group

Journal:

Year:

1998

Language:

english

File:

PDF, 367 KB

english, 1998

5

Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and L-arginine in patients with arteriogenic and non-arteriogenic erectile dysfunction

R. Paroni, A. Barassi, F. Ciociola, E. Dozio, E. Finati, I. Fermo, F. Ghilardi, G. M. Colpi, M. M. Corsi, G. V. Melzi d’Eril

Journal:

International Journal of Andrology

Year:

2012

Language:

english

File:

PDF, 150 KB

english, 2012

6

Leiomyoma pseudocapsule after pre-surgical treatment with gonadotropin-releasing hormone agonists: Relationship between clinical features and immunohistochemical changes

Marianna De Falco, Stefania Staibano, Massimo Mascolo, Chiara Mignogna, Luigi Improda, Francesca Ciociola, Ilma F. Carbone, Andrea Di Lieto

Journal:

European Journal of Obstetrics & Gynecology and Reproductive Biology

Year:

2009

Language:

english

File:

PDF, 327 KB

english, 2009

7

The FDA's Generic-Drug Approval Process: Similarities to and Differences From Brand-Name Drugs

Kefalas, Costas H, Ciociola, Arthur A

Journal:

American Journal of Gastroenterology

Year:

2011

Language:

english

File:

PDF, 104 KB

english, 2011

8

[IEEE 2017 IEEE SmartWorld, Ubiquitous Intelligence & Computing, Advanced & Trusted Computed, Scalable Computing & Communications, Cloud & Big Data Computing, Internet of People and Smart City Innovation (SmartWorld/SCALCOM/UIC/ATC/CBDCom/IOP/SCI) - San Francisco, CA, USA (2017.8.4-2017.8.8)] 2017 IEEE SmartWorld, Ubiquitous Intelligence & Computing, Advanced & Trusted Computed, Scalable Computing & Communications, Cloud & Big Data Computing, Internet of People and Smart City Innovation (SmartWorld/SCALCOM/UIC/ATC/CBDCom/IOP/SCI) - UMAP: Urban mobility analysis platform to harvest car sharing data

Ciociola, Alessandro, Cocca, Michele, Giordano, Danilo, Mellia, Marco, Morichetta, Andrea, Putina, Andrian, Salutari, Flavia

Year:

2017

Language:

english

File:

PDF, 772 KB

english, 2017

9

Evaluation of the teratogenicity of morphine sulfate administered via a miniature implantable pump

Arthur A. Ciociola, Ronald F. Gautieri

Journal:

Journal of Pharmaceutical Sciences

Year:

1983

Language:

english

File:

PDF, 546 KB

english, 1983

10

Effects of ranitidine bismuth citrate on gastric acid secretion and gastrin release in subjects with and without Helicobacter pylori infection

A. A. CIOCIOLA, D. D. WEBB, A. HEATH, J. H. WALSH

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 173 KB

english, 1996

11

Low-dose ranitidine for the relief of heartburn

PAPPA, GOOCH, BUARON, PAYNE, GIEFER, SIRGO, CIOCIOLA

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 138 KB

english, 1999

12

A double-blind, placebo-controlled study of the efficacy and safety of non-prescription ranitidine 75 mg in the prevention of meal-induced heartburn

PAPPA, WILLIAMS, PAYNE, BUARON, MUSSARI, CIOCIOLA

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 219 KB

english, 1999

13

Managing heartburn at the ‘base’ of the GERD ‘iceberg’: effervescent ranitidine 150 mg b.d. provides faster and better heartburn relief than antacids

Earnest, Robinson, Rodriguez-Stanley, Ciociola, Jaffe, Silver, Kleoudis, Murdock

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2000

Language:

english

File:

PDF, 245 KB

english, 2000

14

Synergy between low-dose ranitidine and antacid in decreasing gastric and oesophageal acidity and relieving meal-induced heartburn

M. Robinson, S. Rodriguez-Stanley, A. A. Ciociola, J. Filinto, S. Zubaidi, P. B. Miner JR, J. D. Gardner

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2001

Language:

english

File:

PDF, 862 KB

english, 2001

15

Effects of antacid formulation on postprandial oesophageal acidity in patients with a history of episodic heartburn

M. Robinson, S. Rodriguez-Stanley, P. B. Miner, A. J. McGuire, K. Fung, A. A. Ciociola

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 399 KB

english, 2002

16

Ranitidine, 75 mg, over-the-counter dose: pharmacokinetic and pharmacodynamic effects in children with symptoms of gastro-oesophageal reflux

S. R. Orenstein, J. L. Blumer, H. M. Faessel, J. A. McGuire, K. Fung, B. U. K. Li, J. E. Lavine, J. E. Grunow, W. R. Treem, A. A. Ciociola

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

17

Determination of the time of onset of action of ranitidine and famotidine on intra-gastric acidity

J. D. Gardner, A. A. Ciociola, M. Robinson, R. L. Mcisaac

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 215 KB

english, 2002

18

FromPichia anomalakiller toxin through killer antibodies to killer peptides for a comprehensive anti-infective strategy

Luciano Polonelli, Walter Magliani, Tecla Ciociola, Laura Giovati, Stefania Conti

Journal:

Antonie van Leeuwenhoek

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011

19

A single dose of ranitidine 150 mg modulates oesophageal acid sensitivity in patients with functional heartburn

S. Rodriguez-Stanley, A. A. Ciociola, S. Zubaidi, H. M. Proskin, P. B. Miner Jr

Journal:

Alimentary Pharmacology & Therapeutics

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

20

Treatment of erectile dysfunction reduces psychological distress

Massimo Bocchio, Fiore Pelliccione, Radu Mihalca, Francesco Ciociola, Stefano Necozione, Alessandro Rossi, Felice Francavilla, Sandro Francavilla

Journal:

International Journal of Andrology

Year:

2009

Language:

english

File:

PDF, 79 KB

english, 2009

21

Seminal macrophages in ejaculates from men with couple infertility

Fiore Pelliccione, Anatolia D’Angeli, Giuliana Cordeschi, Radu Mihalca, Francesco Ciociola, Stefano Necozione, Felice Francavilla, Sandro Francavilla

Journal:

International Journal of Andrology

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

22

Second Degree SA Block and Escape-Capture Bigeminy Diagnosed by Esophageal Electrocardiography

GIOVANNI CAMPANALE, GIULIANO CIOCIOLA, ANTONIO SCARCIA, RITA SALIANI, ADRIANO SIVO, FRANCESCO GIRARDI

Journal:

Journal of Cardiovascular Electrophysiology

Year:

1987

Language:

english

File:

PDF, 1.41 MB

english, 1987

23

Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth

Migliaccio, A, Varricchio, L, De Falco, A, Castoria, G, Arra, C, Yamaguchi, H, Ciociola, A, Lombardi, M, Di Stasio, R, Barbieri, A

Journal:

Year:

2007

Language:

english

File:

PDF, 334 KB

english, 2007

24

Crosstalk between EGFR and Extranuclear Steroid Receptors

ANTIMO MIGLIACCIO, GABRIELLA CASTORIA, MARINA DI DOMENICO, ALESSANDRA CIOCIOLA, MARIA LOMBARDI, ANTONIETTA DE FALCO, MERLIN NANAYAKKARA, DANIELA BOTTERO, ROSINA DE STASIO, LILIAN VARRICCHIO, FERDINAND

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 165 KB

english, 2006

25

Control of Nocturnal Gastric Acidity: A Role for Low Dose Bedtime Ranitidine to Supplement Daily Omeprazole

Malcolm Robinson, Sheila Rodriguez-Stanley, Arthur A. Ciociola, Jonathan Filinto, Sattar Zubaidi, Philip B. Miner, Jerry D. Gardner

Journal:

Digestive Diseases and Sciences

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

26

Ranitidine Bismuth Citrate Plus Clarithromycin: A Dual Therapy Regimen for Patients with Duodenal Ulcer

Frank L. Lanza, Stephen J. Sontag, Arthur A. Ciociola, Deborah L. Sykes, Amy Heath, David J. McSorley

Journal:

Year:

1998

Language:

english

File:

PDF, 434 KB

english, 1998

27

GR 38032F (Ondansetron), a selective 5HT3receptor antagonist, slows colonic transit in healthy man

N. J. Talley, S. F. Phillips, A. Haddad, L. J. Miller, C. Twomey, A. R. Zinsmeister, R. L. MacCarty, A. Ciociola

Journal:

Digestive Diseases and Sciences

Year:

1990

Language:

english

File:

PDF, 386 KB

english, 1990

28

Effect of selective 5HT3antagonist (GR 38032F) on small intestinal transit and release of gastrointestinal peptides

N. J. Talley, S. F. Phillips, A. Haddad, L. J. Miller, C. Twomey, A. R. Zinsmeister, A. Ciociola

Journal:

Digestive Diseases and Sciences

Year:

1989

Language:

english

File:

PDF, 482 KB

english, 1989

29

The potential of NeemAzal for the control of coffee leaf pests

Madelaine Venzon, Maria Consolação Rosado, Marcos Antônio Matiello Fadini, Américo Iorio Ciociola Jr, Angelo Pallini

Journal:

Crop Protection

Year:

2005

Language:

english

File:

PDF, 592 KB

english, 2005

30

Teratogenic and Behavioral Anomalies Induced by Acute Exposure of Mice to Ethanol and Their Possible Relation to Fetal Brain DNA Synthesis

Arthur A. Ciociola, Ronald F. Gautieri

Journal:

Pharmaceutical Research

Year:

1988

File:

PDF, 1.54 MB

1988

31

Immunohistochemical detection of insulin-like growth factor type I receptor and uterine volume changes in gonadotropin-releasing hormone analog-treated uterine leiomyomas

Andrea Di Lieto, Francesca Iannotti, Marianna De Falco, Stefania Staibano, Fabrizio Pollio, Francesca Ciociola, Gaetano De Rosa

Journal:

American Journal of Obstetrics and Gynecology

Year:

2003

Language:

english

File:

PDF, 428 KB

english, 2003

32

ORIGINAL RESEARCH—ERECTILE DYSFUNCTION: Evaluation of Microalbuminuria in Patients with Erectile Dysfunction

Alessandra Barassi, Raffaele Pezzilli, Antonio Maria Morselli-Labate, Wanda Porreca, Guido Piediferro, Francesco Ciociola, Giovanni Colpi, GianVico Melzi D'Eril

Journal:

The Journal of Sexual Medicine

Year:

2010

Language:

english

File:

PDF, 86 KB

english, 2010

33

Utrastructural analysis of asthenozoospermic ejaculates in the era of assisted procreation

Sandro Francavilla, Fiore Pelliccione, Giuliana Cordeschi, Stefano Necozione, Riccardo Santucci, Massimo Bocchio, Radu Mihalca, Francesco Ciociola, Felice Francavilla

Journal:

Fertility and Sterility

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

34

Gender-dependent association of type 2 diabetes with the vasoactive intestinal peptide receptor 1

Fabiana Paladini, Valerio Adinolfi, Elisa Cocco, Ester Ciociola, Giulia Tamburrano, Isabella Cascino, Federica Lucantoni, Susanna Morano, Rosa Sorrentino

Journal:

Year:

2012

Language:

english

File:

PDF, 147 KB

english, 2012

35

Antegrade Subinguinal Sclerotization With Temporary Clamping of the Spermatic Cord: A New Surgical Technique for Varicocele

Mario Mancini, Luca Carmignani, Ashok Agarwal, Francesco Ciociola, Fabio Pasqualotto, M. Fabrizio Castiglioni, Guido Piediferro, Giovanni M. Colpi

Journal:

Year:

2011

Language:

english

File:

PDF, 341 KB

english, 2011

36

Transcriptional response to GAA deficiency (Pompe disease) in infantile-onset patients

A.T. Palermo, R.E. Palmer, K.S. So, S.M. Oba-Shinjo, M. Zhang, B. Richards, S.T. Madhiwalla, P.F. Finn, A. Hasegawa, K.M. Ciociola, M. Pescatori, A.J. McVie-Wylie, R.J. Mattaliano, S.L. Madden, S.K.N.

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 2.86 MB

english, 2012

37

A double-masked, placebo-controlled study of the efficacy and safety of premeal ranitidine in the prevention or reduction of heartburn

Keith A. Pappa, Kathy S. Buaron, Malijana Mandich, Mark A. Sirgo, Benjamin O. Williams, J.Ellen Payne, Lori A. Witham, Arthur A. Ciociola

Journal:

Current Therapeutic Research

Year:

1998

Language:

english

File:

PDF, 849 KB

english, 1998

38

Daily or severe heartburn predicts a favorable response to ranitidine 150 MG bid in otherwise healthy antacid users

D.L. Earnest, M. Robinson, S. Rodriguez-Stanley, A. Ciociola

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 165 KB

english, 1998

39

Genetic determinants and early carotid atherosclerosis: is there a role for the ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP-1) K121Q polymorphism? Preliminary results in non diabetic individuals

Coletta, P., Barbarossa, G., Pergolini, D., D’Erasmo, L., Renzi, A., Mercuri, L., Anatra, M. G., Ciociola, E., Verrienti, A., Maranghi, M.

Journal:

Endocrine (Springer)

Year:

2012

Language:

english

File:

PDF, 169 KB

english, 2012

40

Attentional cortical responses to enlarged faces are related to body fat in normal weight subjects: An electroencephalographic study

Claudio Babiloni, Claudio Del Percio, Mario De Rosas, Anna Valenzano, Fabrizio Vecchio, Nicola Marzano, Carla Rendina, Claudia Di Santo, Luisa Ciociola, Brunello Lecce, Ciro Mundi, Fabrizio Eusebi, Gi

Journal:

Clinical Neurophysiology

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

41

Integrated acidity: a novel technique demonstrating synergy between low dose ranitidine and antacid for acid reduction and relief of meal-induced heartburn

Malcolm Robinson, Sheila Rodriguez-Stanley, Arthur A Ciociola, Jonathan Filinto, Sattar Zubaidi, Philip B Miner Jr., Jerry D Gardner

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 30 KB

english, 2000

42

Esophageal acid sensitivity modulates response to acid reducing therapy in postprandial heartburn

Sheila Rodriguez-Stanley, Malcolm Robinson, Arthur A Ciociola, Jonathan Filinto, Sattar Zubaidi, Philip B Miner Jr., Jerry D Gardner

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 37 KB

english, 2000

43

Integrated acidity and heartburn severity determine timing of self-medication in postprandial heartburn

Malcolm Robinson, Sheila Rodriguez-Stanley, Arthur A Ciociola, Jonathan Filinto, Sattar Zubaidi, Philip B Miner Jr., Jerry D Gardner

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 30 KB

english, 2000

44

Direct neutralization of esophageal acid by antacid in meal-induced heartburn

Malcolm Robinson, Sheila Rodriguez-Stanley, Arthur A Ciociola, Jonathan Filinto, Sattar Zubaidi, Philip B Miner Jr., Jerry D Gardner

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 30 KB

english, 2000

45

Precise determination of the onset of action of different gastric antisecretory agents

Richard L McIsaac, Arthur A Ciociola, Malcolm M Robinson, Jerry D Gardner

Journal:

American Journal of Gastroenterology

Year:

2001

Language:

english

File:

PDF, 38 KB

english, 2001

46

In vivo gastric autotitration: a novel, simple method to measure meal-stimulated gastric acid secretion

Jerry D Gardner, Arthur A Ciociola, Jonathan Filinto, Malcolm Robinson

Journal:

American Journal of Gastroenterology

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

47

Meal-stimulated gastric acid secretion in healthy subjects correlates with postprandial but not fasting gastric acidity

Jerry D Gardner, Arthur A Ciociola, Jonathan Filinto, Malcolm Robinson

Journal:

American Journal of Gastroenterology

Year:

2001

Language:

english

File:

PDF, 35 KB

english, 2001

48

Prevention of moderate-to-severe meal-induced heartburn: ranitidine 150mg is superior to ranitidine 75mg when taken immediately before the meal

Arthur A Ciociola, Wieslaw Bochenek, Richard L McIsaac, J.Anthony McGuire, Malcolm Robinson

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 26 KB

english, 2002

49

Are patients with functional heartburn sensitive to both mechanical and chemical stimuli?

Sheila Stanley-Rodriguez, Sattar Zubaidi, Arthur Ciociola, Philip B. Miner Jr

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 37 KB

english, 2002

50

Barostat balloon distention of the esophagus: pressure-ramp vs volume-step for determination of sensation and pain thresholds

Sheila Rodriguez-Stanley, Sattar Zubaidi, Arthur Ciociola, Philip B Miner Jr

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 25 KB

english, 2002

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